Activating Compound | Comment | Organism | Structure |
---|---|---|---|
testosterone | left ventricle HSL activity against triglycerides is significantly elevated in intact rats supplemented with testosterone, testosterone replacement fully reverses this effect | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Rattus norvegicus | - |
left ventricle | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-dioleoyl-sn-glycerol + H2O | - |
Rattus norvegicus | 2-oleoylglycerol + oleate | - |
? | |
triolein + H2O | - |
Rattus norvegicus | diolein + oleate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HSL | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | hormone-sensitive lipase regulates triglycerides breakdown under hormonal control. Left ventricle HSL activity against triglycerides is significantly elevated in intact rats supplemented with testosterone | Rattus norvegicus |